White matter abnormalities in a patient with visual snow syndrome: New evidence from a diffusion tensor imaging study

Background Visual snow syndrome (VSS) is a neurological condition characterized by flickering dots throughout the entire visual field. Both pathophysiology and possible location of VSS are still under debate. White matter abnormalities were investigated using diffusion tensor imaging (DTI) in patient with VSS. Methods A 28-year-old 10 healthy controls DTI. Diffusion parametric maps calculated reconstructed q-space diffeomorphic reconstruction. pathways dorsal, ventral, integrative streams thalamic connectivity tracked. Then, they applied to each subject's parameter map, stretched same length, sampled along tracts for regional analyses DTI parameters. Results Compared controls, our displayed higher axial diffusivity (AD) radial (RD) dorsal stream (cingulum, arcuate fasciculus, horizontal indirect anterior segment superior longitudinal fasciculus), ventral (fronto-occipital inferior fasciculus) (indirect posterior component vertical occipital fasciculus). Higher AD RD also detected acoustic optic radiations, radiations distal thalamus. Conclusion This multiple, bilateral white changes temporo-parieto-occipital junction related vision. We encourage study pathology complex syndromes including